BEIJING--U.S. Secretary of State Antony Blinken is set to meet with Chinese President Xi Jinping on Monday, wrapping up a rare and pivotal trip to Beijing that aimed at ensuring the many disputes between the superpowers do not spiral into conflict.

Blinken’s meeting with Xi on the final day of his two-day visit will be the first time a U.S. secretary of state has met the Chinese leader since 2018, and it could help to facilitate a summit between Xi and U.S. President Joe Biden later in the year.

“Secretary Blinken will meet with People’s Republic of China President Xi Jinping at 4:30 p.m (0830 GMT),” a State Department official said.

Making the first visit to China by a U.S. secretary of state in five years, Blinken held extensive discussions with China’s top diplomat Wang Yi on Monday, and foreign minister Qin Gang on Sunday.

The talks, held at the Diaoyutai state guest house in Beijing, did not appear to make much progress in bridging the two sides’ differences on issues ranging from Taiwan to trade, human rights, stemming the flow of synthetic opioid fentanyl or their approach to the war in Ukraine.

Describing the U.S.-China relationship as being at a low point, Wang said the root cause was the United States’ wrong perception of China. Blinken underscored the importance of open communication channels to manage their competition during more than three hours of talks with Wang, the State Department said, calling their conversation as “productive.”

“We must take a responsible attitude toward the people, history and the world, and reverse the downward spiral of U.S.-China relations,” Wang said during the meeting with Blinken, according to a statement released by China’s foreign ministry.

Wang urged the United States to stop speculating on threats from China, abandon its “suppression” of China’s scientific and technological development, and refrain from interfering in its internal affairs, according to Chinese state media.

The lack of regular and open communication channels between the world’s top two economies has sent jitters around the world. Beijing’s reluctance to engage in regular military-to-military talks with Washington has alarmed China’s neighbors.

During 7-1/2 hours of talks with Qin on Sunday, Blinken stressed “the need to reduce the risk of misperception and miscalculation”, the State Department said.

Both sides emphasized the importance of making it easier for their citizens to visit, and agreed on working to increase passenger flights, which boosted Chinese airline shares.

They also expressed a desire to stabilize bilateral ties despite what one U.S. official called their “profound” differences and agreed that Qin would visit Washington to continue the conversation, though no date was announced.

“This is going to be a process of sustained diplomacy,” one senior State Department official, speaking on the condition of anonymity, said on Sunday.

Blinken’s trip, which was postponed in February after a suspected Chinese spy balloon flew over U.S. airspace, is closely followed worldwide as further deterioration of ties between the world’s two largest economies could have global implications on financial markets, trade practices and routes and supply chains.

TAIWAN CORE ISSUE

Beijing’s tone on Taiwan, the democratic island Beijing claims as it own, has been particularly pointed throughout Blinken’s visit. Wang said “China has no room for compromise or concessions”, according to the Chinese readout.

The United States has long stuck to a policy of “strategic ambiguity” over whether it would respond militarily to an attack on Taiwan, which Beijing has refused to rule out.

When asked last year, U.S. President Joe Biden said Washington would defend Taiwan in the event of a Chinese invasion, though aides later said his comments did not reflect a policy departure from the long-standing “one China” policy.

U.S. officials have underscored that the United States does not support Taiwan independence.

The Chinese readout of Sunday’s meetings described them as constructive but made clear that Taiwan is the most important issue, and a potentially dangerous one.

“Qin Gang pointed out that the Taiwan issue is the core of China’s core interests, the most important issue in Sino-US relations, and the most prominent risk,” Chinese state media quoted Qin as having told the top U.S. diplomat.

U.S. officials have been playing down the prospect of a major breakthrough in talks, but they and analysts expect Blinken’s visit will pave the way for more bilateral meetings in coming months, including possible trips by Treasury Secretary Janet Yellen and Commerce Secretary Gina Raimondo.

Biden and Xi held long-awaited first face-to-face talks on the sidelines of a summit of the Group of 20 big economies in November on the Indonesian island of Bali, engaging in blunt talks over Taiwan and North Korea but also pledging more frequent communication, although ties since then have deteriorated.